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Fig. 3 | EURASIP Journal on Bioinformatics and Systems Biology

Fig. 3

From: MOBAS: identification of disease-associated protein subnetworks using modularity-based scoring

Fig. 3

Two significant subnetworks. a Top subnetwork and b second top subnetwork that are found to be significantly associated with T2D. The size of each node indicates the significance of the association of the corresponding protein with T2D (r v ). The diamond nodes are those previously reported to be associated with T2D in the literature [28]. The intensity of purple coloring in the nodes indicates the number of computational disease gene prioritization methods [29] that identified the respective gene to be associated with T2D. The individual p values of each gene in the subnetwork are shown in the table left of the subnetwork. The genes with insignificant p value (p>0.05) that are known to be related to T2D are highlighted in yellow. The genes with insignificant p value and are not reported to be related to T2D are highlighted in orange. These genes are the candidates for further investigation

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