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Table 2 Interaction site prediction performance of different models

From: Enhancing interacting residue prediction with integrated contact matrix prediction in protein-protein interaction

 

Avg. accuracy (%)

Avg. F1 (%)

Avg. MCC (%)

Avg. precision (%)

Avg. recall (%)

ipHMM

94.93

75.61

73.69

77.56

76.51

CM-ipHMM

96.97

90.05

89.11

85.98

96.83

CM-only

96.30

88.52

87.23

85.22

94.91

Ground-truth-CM

99.83

99.51

99.40

99.89

99.21

  1. ipHMM the interaction profile hidden Markov model used to prediction interaction site, CM-ipHMM the logistic regression model built with the integration of contact matrix prediction and ipHMM interaction site prediction, CM-only the logistic regression model built with the predicted contact matrix prediction only, Ground-truth-CM the logistic regression model built with the ground-truth contact matrix prediction and ipHMM interaction site prediction