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Table 2 Interaction site prediction performance of different models

From: Enhancing interacting residue prediction with integrated contact matrix prediction in protein-protein interaction

  Avg. accuracy (%) Avg. F1 (%) Avg. MCC (%) Avg. precision (%) Avg. recall (%)
ipHMM 94.93 75.61 73.69 77.56 76.51
CM-ipHMM 96.97 90.05 89.11 85.98 96.83
CM-only 96.30 88.52 87.23 85.22 94.91
Ground-truth-CM 99.83 99.51 99.40 99.89 99.21
  1. ipHMM the interaction profile hidden Markov model used to prediction interaction site, CM-ipHMM the logistic regression model built with the integration of contact matrix prediction and ipHMM interaction site prediction, CM-only the logistic regression model built with the predicted contact matrix prediction only, Ground-truth-CM the logistic regression model built with the ground-truth contact matrix prediction and ipHMM interaction site prediction