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Table 9 Conditional probability tables for gene nodes of \(\mathcal {M}_{\text {PBK+EI}}\)

From: A pedagogical walkthrough of computational modeling and simulation of Wnt signaling pathway using static causal models in MATLAB

   Conditional probability table for nodes
Node Parents Cpt values rep.
L E F1 Sample [0.84 0.16; 0.16 0.84] T
MYC Sample, [0.94 0.89 0.78 0.31;
  TRCMPLX 0.06 0.11 0.22 0.69] T
C C N D1 Sample, [0.95 0.89 0.81 0.28;
  TRCMPLX 0.06 0.11 0.18 0.72] T
C D44 Sample, [0.93 0.90 0.67 0.42;
  TRCMPLX 0.07 0.10 0.33 0.58] T
D K K1 Sample, [0.95 0.93 0.07 0.05 0.77 0.60 0.40 0.23;
  M e D K K1, 0.05 0.07 0.93 0.95 0.23 0.40 0.60 0.76] T
  TRCMPLX  
D K K2 Sample [0.40 0.60; 0.60 0.40] T
D K K3-1 Sample [0.36 0.64; 0.64 0.36] T
D K K3-2 Sample [0.56 0.44; 0.44 0.56] T
D K K4 Sample, [0.94 0.88 0.82 0.28;
  TRCMPLX 0.06 0.11 0.18 0.72] T
D A C T1 Sample, [0.56 0.74 0.26 0.44;
  M e D A C T1 0.44 0.26 0.74 0.56] T
D A C T2 Sample, [0.60 0.71 0.29 0.40;
  M e D A C T2 0.40 0.29 0.71 0.60] T
D A C T3 Sample, [0.88 0.88 0.12 0.88 0.88 0.88 0.12 0.88;
  H3K27m e3, 0.12 0.12 0.88 0.12 0.12 0.12 0.88 0.12] T
  H3K4m e3  
S F R P1 Sample, [0.88 0.98 0.02 0.12 0.20 0.96 0.04 0.80;
  M e S F R P1, 0.12 0.02 0.98 0.88 0.80 0.04 0.96 0.20] T
  TRCMPLX  
S F R P2 Sample, [0.31 0.88 0.11 0.69;
  M e S F R P2 0.69 0.11 0.89 0.31] T
S F R P3 Sample [0.20 0.80; 0.80 0.20] T
S F R P4 Sample, [0.71 0.60 0.40 0.29;
  M e S F R P4 0.29 0.40 0.60 0.71] T
S F R P5 Sample, [0.31 0.89 0.11 0.69;
  M e S F R P5 0.69 0.11 0.89 0.31] T
W I F1 Sample, [0.96 0.91 0.09 0.04 0.85 0.47 0.56 0.15;
  M e W I F1, 0.04 0.09 0.91 0.96 0.15 0.53 0.47 0.85] T
  TRCMPLX  
  1. The state of the gene nodes remains [ia a], i.e., “ia” - inactive or “a” - active [ia a]. Note that these values are from one iteration of the 2-holdout experiment