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Table 8 Conditional probability tables for nodes (excluding gene expression) of \(\mathcal {M}_{\text {PBK+EI}}\)

From: A pedagogical walkthrough of computational modeling and simulation of Wnt signaling pathway using static causal models in MATLAB

   Conditional probability table for nodes  
Node Parents Cpt values rep. Node states
Sample - [0.50 0.50] T [n t]
T C F4 - [0.10 0.90] T [ia a]
D V L2 D A C T3 [0.01 0.99; 0.99 0.01] T [lc hc]
β-catenin D A C T1, [0.99 0.99 0.99 0.01; [lc hc]
  D V L2 0.01 0.01 0.01 0.99] T  
TRCMPLX T C F4, L E F1, [0.99*ones(1,7) 0.01; [ia a]
  β-catenin 0.01*ones(1,7) 0.99] T  
M e D A C T1 - [0.8370 0.1630] T [nm m]
M e D A C T2 - [0.3376 0.6624] T [nm m]
M e W I F1 - [0.1667 0.8333] T [nm m]
M e S F R P1 - [0.6316 0.3684] T [nm m]
M e S F R P2 - [0.6316 0.3684] T [nm m]
M e S F R P4 - [0.8572 0.1428] T [nm m]
M e S F R P5 - [0.7500 0.2500] T [nm m]
H3K27m e3 - [0.2391 0.7609] T [ia a]
H3K4m e3 - [0.3661 0.6339] T [ia a]
  1. Notations in the table mean the following “-” implies no parents exist for the particular node; “n” - normal, “t” - tumorous, “ia” - inactive, “a” - active, “lc” - low concentration, “hc” - high concentration, “nm” - non-methylated, “m” - methylation