Skip to main content

Advertisement

Table 1 Specificity of siRNA target prediction

From: shRNA target prediction informed by comprehensive enquiry (SPICE): a supporting system for high-throughput screening of shRNA library

shRNA (passenger) Target Reference Target predicted by the SPICEa
GAUUAUCCAAAGAGGUUCU RPS6KA6 Berns et al. [2] RPS6KA6 (1, 0)
UGGUUGAUGAGCCAAUGGA RPS6KA6 Berns et al. [2] RPS6KA6 (1, 0)
GUACGGCCGUAGUCUCAAG HTATIP Berns et al. [2] KAT5 (1, 0): identical to HTATIP
CAAACGUCUGGAUGAAUGG HTATIP Berns et al. [2] KAT5 (1, 0): identical to HTATIP
GCCAUCCAGAUGGACUUUC HDAC4 Berns et al. [2] HDAC4 (1, 0)
GCAUGUGUUUCUGCCUUGC HDAC4 Berns et al. [2] HDAC4 (1, 0)
GCAGCAGAGGUGAUUCUGC CCT2 Berns et al. [2] CCT2 (1, 0)
GAGAGGCGCUGUUGAGUUC CCT2 Berns et al. [2] CCT2 (1, 0)
GAGUACAUUCUGCCUUGCU KIAA0828 Berns et al. [2] AHCYL2 (1, 0): identical to KIAA0828
GCUACAUCAAGAACUCAGC KIAA0828 Berns et al. [2] AHCYL2 (1, 0): identical to KIAA0828
GAGACCTACCTCCGGATCA PLK1 Jackson et al. [16] PLK1 (1, 0)
  1. aNumbers in parentheses show (target genes, mismatches in alignment)