Skip to main content


Fig. 9 | EURASIP Journal on Bioinformatics and Systems Biology

Fig. 9

From: Carcinogenesis: alterations in reciprocal interactions of normal functional structure of biologic systems

Fig. 9

Two hierarchical levels of stem cell differentiation. Asymmetric cell division is resulted in splitting of the character A on two daughter characters A 1 and A 2 linked by reciprocal interactions (RL). Other characters may remain unchanged. Different stages of cell maturation are linked by negative feedback (NFB) sending inhibitory signals to the pool of cell progenitors

Back to article page