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EURASIP Journal on Bioinformatics and Systems Biology
Fig. 9 | EURASIP Journal on Bioinformatics and Systems Biology

Fig. 9

From: Carcinogenesis: alterations in reciprocal interactions of normal functional structure of biologic systems

Fig. 9

Two hierarchical levels of stem cell differentiation. Asymmetric cell division is resulted in splitting of the character A on two daughter characters A 1 and A 2 linked by reciprocal interactions (RL). Other characters may remain unchanged. Different stages of cell maturation are linked by negative feedback (NFB) sending inhibitory signals to the pool of cell progenitors

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