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Table 2 Summary of control results for the mutated cell-cycle network

From: Molecular network control through boolean canalization

Control action

Outcome

Delete E2F →CycE

Single fixed point

 

with p27=Cdh1=1

Delete Cdh1 →Ubc

>90 % of states in component

 

with fixed point where

 

p27=Cdh1=1

Express constantly

Two fixed points,

CycB →E2F

both with p27=Cdh1=1

Express constantly

>90 % of states in component

Cdc20 →CycA

with fixed point where

 

p27=Cdh1=1