Table 2 Statistical significance (q value) of top subnetworks. The subnetworks are identified using MOBAS according to the permuted genotype and PPI on two independent psoriasis datasets
From: MOBAS: identification of disease-associated protein subnetworks using modularity-based scoring
Rank | GAIN - PS | WTCCC - PS | ||||
|---|---|---|---|---|---|---|
Size | q value in | q value in | Size | q value in | q value in | |
permuted genotype | permuted PPI networks | permuted genotype | permuted PPI networks | |||
1 | 13 | <0.01 | <0.01 | 15 | <0.01 | 0.05 |
2 | 8 | <0.01 | <0.01 | 26 | <0.01 | 0.06 |
3 | 9 | 0.01 | 0.23 | 10 | <0.01 | 0.12 |
4 | 6 | 0.02 | 0.38 | 9 | <0.01 | 0.14 |
5 | 9 | 0.02 | 0.33 | 30 | <0.01 | 0.47 |
6 | 5 | 0.02 | 0.33 | 5 | <0.01 | 0.51 |
7 | 4 | 0.04 | 0.33 | 12 | <0.01 | 0.49 |