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Table 3 Regulatory relationships of a p53 signaling network

From: Optimal cancer prognosis under network uncertainty

Gene/protein/signal Predictors: regulatory type (+ / −)
DNAdamage DNAdamage: +
p53 ATR: +, CHEK1: +, CHEK2: +,
  MDM2: −, MDMX: −
p14ARF p14ARF: +
ATR DNAdamage: +
ATM DNAdamage: +
CHEK1 ATR: +
CHEK2 ATM: +
MDM2 p14ARF: −, MDMX: +
MDMX MDM2: −