From: Modeling and systematic analysis of biomarker validation using selected reaction monitoring
Parameter | Defaults value |
---|---|
Number of classes | 2 |
Sample size | n=80 |
Block size | b=5 |
Block correlation | ρ=0.8 |
Fold change | h=2, a i ∼U n i f(1,2) |
Modification noise | αpm=0.03,βpm=3.6 |
Peptide efficiency factor | αpe=0.5,e i ∼U(0.5,1) |
Gamma parameters | t c =2,θ c =100,t a =5,θ a =10e 6 |
Purification | β γ =10e−6 |
Protein mixture |
|
Ranking power | d=2, r=0.01 |