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EURASIP Journal on Bioinformatics and Systems Biology

Table 5 Notable leukemia network templates

From: Template-based intervention in Boolean network models of biological systems

Basin

Rank

Variables

Values

F j,i

Success

1

18

Ceramide

0

22,936

0.73 a

  

PDGFR

1

  
  

S1P

0

  

2

27

PDGFR

0

28,057

1.00

  

S1P

0

  
  

TBET

1

  

3

1

Ceramide

0

14,404

1.00

  

PDGFR

1

  
  

S1P

1

  

4

6

TBET

0

6,404

0.73

  1. aRemaining 27% of interventions lead Basin 4 (also healthy). Listed in the table is a selection of interesting templates from the analysis of the leukemia network. Complete lists of the top frequency templates for each basin and each template size can be found in Additional file 3.
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