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Table 3 P values for two-proportion Z -tests

From: Template-based intervention in Boolean network models of biological systems

 

10E/10S

12E/12S

18E/18S

POP

0.0920

0.4619

0.0000

POW

0.0013

0.0003

0.0000

HPP

0.0000

0.2030

0.0000

K1TBDP

0.0000

0.0000

0.0000

K2TDBP

0.0007

0.4421

0.0000

K3TDBP

0.0002

0.4391

0.0000

K4TBDP

0.5424

0.1385

0.0000

K1FREQ

0.2197

0.0002

0.2038

K2FREQ

0.0004

0.0000

0.3964

K3FREQ

0.2015

0.0000

0.0192

K4FREQ

0.0062

0.0014

0.2310

  1. In the table, we see the P values for two-proportion Z-tests across 11 intervention targets between exhaustively enumerated (E) and sampled (S) networks with 10, 12, and 18 variables. For P values below the α=0.05 significance level, we reject the null hypothesis and conclude that there exists a statistically significant difference in success proportions between the exhaustive and the sampled state space cases. These differences can be inspected visually in Figure 3.