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EURASIP Journal on Bioinformatics and Systems Biology
Figure 3 | EURASIP Journal on Bioinformatics and Systems Biology

Figure 3

From: Protein network-based Lasso regression model for the construction of disease-miRNA functional interactions

Figure 3

Comparative analysis using different integrative biology approaches. AUC using different inputs in different cancer types. We compared the ROC results from different combinations of inputs. Integrating multiple data to define disease gene signatures and including protein networks to define miRNA signature improves the accuracy of the model. Different miRNA-target interaction data leads to different results. This is due to the completeness of miRNA-target interactions.

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