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Table 2 The SFHs of which copy number status were associated with patient survival

From: Identification of genomic functional hotspots with copy number alteration in liver cancer

Chr

Start pos

End pos

p value

 

Presented gene set

Number of overlapped genes

Gain

      

 19

41.38

41.63

2.6E-04

mf

Oxygen binding

2

 19

43.23

44.29

0.001

bp

Defense response

4

 19

54.72

55.11

0.002

bp

Defense response

6

 19

54.72

55.11

0.002

bp

Cell surface receptor linked Signaling pathway

6

 19

40.09

40.23

0.003

mf

Lysophospholipase activity

2

 19

40.09

40.23

0.003

mf

Carboxylesterase activity

2

 19

39.41

39.52

0.004

cc

SCF ubiquitin ligase complex

2

 19

39.41

39.52

0.004

mf

Glycoprotein binding

2

 19

51.63

52.15

0.007

mf

Sugar binding

9

 19

54.78

55.38

0.007

bp

Regulation of immune response

8

 19

51.63

52.27

0.007

bp

Cell adhesion

11

 19

42.18

44.32

0.007

cc

Anchored to membrane

9

 19

54.72

55.55

0.007

mf

Transmembrane receptor activity

8

 19

54.80

55.30

0.007

mf

Antigen binding

5

 19

54.78

55.42

0.007

bp

Cellular defense response

5

 19

54.72

55.55

0.007

cc

Integral to plasma membrane

12

 19

58.55

59.08

0.007

bp

Viral reproduction

7

 19

54.78

55.40

0.007

bp

Immune response

6

 19

50.86

51.59

0.008

mf

Peptidase activity

17

 19

45.41

45.45

0.008

mf

Lipid transporter activity

2

Loss

      

 8

11.83

12.18

2.4E-04

bp

Defense response to bacterium

4

 4

55.10

55.99

0.001

bp

Vascular endothelial growth Factor receptor signaling pathway

2

 4

55.10

55.99

0.001

mf

Growth factor binding

2

 8

22.88

23.08

0.001

mf

Caspase activator activity

2

 8

22.30

23.02

0.002

bp

Apoptosis

5

 4

74.61

74.97

0.003

bp

Inflammatory response

5

 8

26.37

27.47

0.004

cc

Growth cone

3

 8

26.37

27.32

0.004

bp

Response to cocaine

2

 8

22.01

23.08

0.005

bp

Cellular response to mechanical stimulus

3

 4

68.69

69.36

0.006

mf

Serine-type endopeptidase activity

5

 4

68.69

69.36

0.006

bp

Proteolysis

5

 4

68.69

69.36

0.006

mf

Peptidase activity

5

 4

70.86

71.40

0.007

bp

Biomineral tissue development

5

 4

71.06

71.47

0.007

bp

Odontogenesis of dentine-containing tooth

3

 4

74.26

74.85

0.007

cc

Platelet alpha granule lumen

3

 4

74.26

74.85

0.007

bp

Platelet degranulation

3

 4

76.92

76.94

0.008

bp

Defense response to virus

2

 4

74.70

75.32

0.008

bp

Cell-cell signaling

4

 8

38.13

38.33

0.008

bp

Cell growth

2