From: Identification of genomic functional hotspots with copy number alteration in liver cancer
Chr | Start pos | End pos | p value | Â | Presented gene set | Number of overlapped genes |
---|---|---|---|---|---|---|
Gain | Â | Â | Â | Â | Â | Â |
 19 | 41.38 | 41.63 | 2.6E-04 | mf | Oxygen binding | 2 |
 19 | 43.23 | 44.29 | 0.001 | bp | Defense response | 4 |
 19 | 54.72 | 55.11 | 0.002 | bp | Defense response | 6 |
 19 | 54.72 | 55.11 | 0.002 | bp | Cell surface receptor linked Signaling pathway | 6 |
 19 | 40.09 | 40.23 | 0.003 | mf | Lysophospholipase activity | 2 |
 19 | 40.09 | 40.23 | 0.003 | mf | Carboxylesterase activity | 2 |
 19 | 39.41 | 39.52 | 0.004 | cc | SCF ubiquitin ligase complex | 2 |
 19 | 39.41 | 39.52 | 0.004 | mf | Glycoprotein binding | 2 |
 19 | 51.63 | 52.15 | 0.007 | mf | Sugar binding | 9 |
 19 | 54.78 | 55.38 | 0.007 | bp | Regulation of immune response | 8 |
 19 | 51.63 | 52.27 | 0.007 | bp | Cell adhesion | 11 |
 19 | 42.18 | 44.32 | 0.007 | cc | Anchored to membrane | 9 |
 19 | 54.72 | 55.55 | 0.007 | mf | Transmembrane receptor activity | 8 |
 19 | 54.80 | 55.30 | 0.007 | mf | Antigen binding | 5 |
 19 | 54.78 | 55.42 | 0.007 | bp | Cellular defense response | 5 |
 19 | 54.72 | 55.55 | 0.007 | cc | Integral to plasma membrane | 12 |
 19 | 58.55 | 59.08 | 0.007 | bp | Viral reproduction | 7 |
 19 | 54.78 | 55.40 | 0.007 | bp | Immune response | 6 |
 19 | 50.86 | 51.59 | 0.008 | mf | Peptidase activity | 17 |
 19 | 45.41 | 45.45 | 0.008 | mf | Lipid transporter activity | 2 |
Loss | Â | Â | Â | Â | Â | Â |
 8 | 11.83 | 12.18 | 2.4E-04 | bp | Defense response to bacterium | 4 |
 4 | 55.10 | 55.99 | 0.001 | bp | Vascular endothelial growth Factor receptor signaling pathway | 2 |
 4 | 55.10 | 55.99 | 0.001 | mf | Growth factor binding | 2 |
 8 | 22.88 | 23.08 | 0.001 | mf | Caspase activator activity | 2 |
 8 | 22.30 | 23.02 | 0.002 | bp | Apoptosis | 5 |
 4 | 74.61 | 74.97 | 0.003 | bp | Inflammatory response | 5 |
 8 | 26.37 | 27.47 | 0.004 | cc | Growth cone | 3 |
 8 | 26.37 | 27.32 | 0.004 | bp | Response to cocaine | 2 |
 8 | 22.01 | 23.08 | 0.005 | bp | Cellular response to mechanical stimulus | 3 |
 4 | 68.69 | 69.36 | 0.006 | mf | Serine-type endopeptidase activity | 5 |
 4 | 68.69 | 69.36 | 0.006 | bp | Proteolysis | 5 |
 4 | 68.69 | 69.36 | 0.006 | mf | Peptidase activity | 5 |
 4 | 70.86 | 71.40 | 0.007 | bp | Biomineral tissue development | 5 |
 4 | 71.06 | 71.47 | 0.007 | bp | Odontogenesis of dentine-containing tooth | 3 |
 4 | 74.26 | 74.85 | 0.007 | cc | Platelet alpha granule lumen | 3 |
 4 | 74.26 | 74.85 | 0.007 | bp | Platelet degranulation | 3 |
 4 | 76.92 | 76.94 | 0.008 | bp | Defense response to virus | 2 |
 4 | 74.70 | 75.32 | 0.008 | bp | Cell-cell signaling | 4 |
 8 | 38.13 | 38.33 | 0.008 | bp | Cell growth | 2 |