Figure 10

Inferred trajectories of the Boolean network for wild type and mutant strains. Inferred trajectories of the Boolean network from [18] for the wild type and mutant strains (one replicate is shown for each). The network structure is displayed at the bottom. Black cells correspond to a Boolean 1 and white cells to a Boolean 0. The corresponding cell cycle stages are marked at the left side of each trajectory. Both trajectories start with active ACE2 and SWI5, which are the last active factors at the completion of the previous cycle, followed activation of CLN3 and an initiation of a new cycle. The network seems to cycle a little faster in the wild type. The network structure was generated using Cytoscape [13].