From: Statistical discovery of site inter-dependencies in sub-molecular hierarchical protein structuring
Cluster | Sites | Highest pattern residual | k | Structural relationship | Functional factors |
---|---|---|---|---|---|
1 | 7,9–11 | 25.9 | 4 | Double bond between 7 and the other sites | 11 is a binding site |
2 | 12,14–17,20 | 57.6 | 6 |  | 12 is adjacent to binding site 11 |
3 | 18–19,21 | 13.4 | 3 | Double bond between 18 and 21 |  |
4 | 23,25–27 | 6.7 | 4 | Double bond between 23 and other sites | 27 is a binding site |
5 | 29–31,41 | 22.6 | 4 | 30 in Van der Waals contact with 41 | 29 is a binding site |
6 | 34–36,38 | 27.9 | 4 | Van der Waals contact 34 & 36 | 34 is adjacent to binding site 33 |
7 | 37,39–40,43 | 20.8 | 4 | 37 bonds to 40 | 43 is adjacent to possible external recognition site 42 and external contact site 44 |
8 | 44–47 | 646.1 | 4 | Van der Waals contact 44 & 47 | sites 44 and 47 are external contact points, 47 is adjacent to major binding site 48 |
9 | 49–50,52 | 7.5 | 3 |  | site 49 is an external contact point |
10 | 54–59 | 31.0 | 6 | 8 internal H-bonds |  |
11 | 60,63–64 | 29.9 | 3 |  | 63 is a major binding site |
12 | 66,68–70 | 27.8 | 4 |  | site 70 is an external contact point |
13 | 43,69,74 | 13.0 | 3 | 43 in tight Van der Waals contact with 69 | 74 is a possible external recognition site |
14 | 70,72–73 | 22.6 | 3 |  | 70 is an external contact point, 73 is an external recognition site |