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Figure 11 | EURASIP Journal on Bioinformatics and Systems Biology

Figure 11

From: Phase computations and phase models for discrete molecular oscillators

Figure 11

Mechanism of PhCompBF (the brute-force phase computation scheme) in time domain for the Brusselator (changes in the molecule number for the species Y are monitored). The star and the circle obtained at the end of the simulations (let us call this time t0) in Figure 10 are fed as initial conditions to the RRE in (11), hence the star and the circle at the beginning of the traces in this figure. The waveforms in this figure monitor the same entry for these two different RRE solutions, i.e., the changes in the molecule number for the species Y are shown. The curve starting with the circle should come to be almost periodic in a matter of a few periods for this oscillator. Then the phase shift between the two waveforms can be computed. This phase shift belongs to the point identified by the circle in Figure 10 at the end of the simulation (we have called this time t0). This phase shift has been obtained with respect to the star in Figure 10 at again the time t0.

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