Figure 12

Drug response at three different schedules but same drug intake: (a–c) the state response at τ = 7,12,22, respectively; (d–f) the state space trajectory at τ = 7,12,22, respectively. Other parameters are $q_1^u=0.1,{\beta }_1=1,{\gamma }_1=0.04,{\theta }_1^{\overline{u}}=10,{\theta }_1^{\underset{‾}{u}}=2,x\left(0\right)=20;p_1=1;p_2=5;{\lambda }_d=0.3$.