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EURASIP Journal on Bioinformatics and Systems Biology
Figure 1 | EURASIP Journal on Bioinformatics and Systems Biology

Figure 1

From: Model-based analysis of an adaptive evolution experiment with Escherichia coli in a pyruvate limited continuous culture with glycerol

Figure 1

Strain F41 malE :: pyc. The mutant F41malE::pyc has a deletion of the two pyruvate kinase (Pyk) genes pykA and pykF, of the phosphoenolpyruvate carboxylase (Ppc) and an insertion of pyruvate carboxylase (Pyc). On the agar plate, F41malE::pyc was not able to grow on glycerol minimal media and was compared to the wild type LJ110 wt. With additional lactate, F41malE::pyc grew. Various endogenous pathways may lead to pyruvate prototrophy.

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