Figure 2From: Relationships between kinetic constants and the amino acid composition of enzymes from the yeast Saccharomyces cerevisiae glycolysis pathwayThe relationships between kinetic constants and frequencies of two AA. The multiple linear regressions showing changes of the log-values of kinetic constants as dependent variables upon the frequencies of occurrence for two AA in the yeast S. cerevisiae sequences, where k cat is the catalytic constant (A), K M is the Michaelis-Menten constant (C), and k sp = k cat/K M is the specificity constant (E). The observed versus predicted plots (B,D,F) for the values of dependent variables (k cat, K M, and k sp, respectively). The predicted values were calculated from the regression equations: log(k cat) = 5.556 –1.620*M −0.984*W (R adj.2 = 82.88%, p = 0.0000); log(K M) = 8.593 –0.596*N −0.998*D (R adj.2 = 53.72%, p = 0.0039); log(k cat/K M) = 0.818 +0.501*A −1.736*H (R adj.2 = 46.50%, p = 0.0068). All the multiple and pair correlations (A–F) are significant at the non-parametric assessment (Kendall's τ, Spearman's ρ correlation coefficients).Back to article page