Figure 6

Comparison of stochastic and deterministic simulations of cAMP dynamics with different initial amounts of Cdc25. The figure shows the dynamics of cAMP with different initial amounts of Cdc25 (150, 200, 300, and 400 molecules) obtained by means of stochastic (left) and deterministic (right) simulations. The deterministic and stochastic behaviors are comparable for Cdc25 equal to 200 and 300 molecules (sustained oscillations occur in both cases) and for Cdc25 equal to 400 (damped oscillations). On the contrary, when the initial amount of Cdc25 is low (i.e., 150 molecules), with the stochastic approach we obtain stable oscillations of cAMP, while in the deterministic case the dynamics shows damped oscillations.