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EURASIP Journal on Bioinformatics and Systems Biology
Figure 2 | EURASIP Journal on Bioinformatics and Systems Biology

Figure 2

From: Weighted next reaction method and parameter selection for efficient simulation of rare events in biochemical reaction systems

Figure 2

Variance σ2 obtained from 107 runs of the wSSAps and the refined wSSA for the system in (32) with c 1 = 0.1, c 2 = 0.1, c 3 = 8, c 4 = 0.1, X 1 (0) = 40, X 2 (0) = 40 and X 3 (0) = 1. wSSAps para 1 represents the wSSAps without fine-tuning the probability of reactions in G3 group; wSSAps para 2 and 3 represent the wSSAps with fine-tuning the probability of reactions in G3 group using two sets of parameters: α = 0.85, β = 0.8 and α = 0.80, β = 0.75. Since the variance of the wSSAps does not depend on δ used in the refined wSSA, it appears as a horizontal line.

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