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Figure 2 | EURASIP Journal on Bioinformatics and Systems Biology

Figure 2

From: Modeling time delay in the NFκB signaling pathway following low dose IL-1 stimulation

Figure 2

Graphical representation of the four model variants. Schematic representation of the original IKKβ phosphorylation model (a) with the extensions positive feedback/TRAF (b), double phosphorylation (c), and irreversible inhibitor (d). Ellipses denote model inputs, boxes with solid lines denote state variables, boxes with dotted lines denote species calculated from mass conservation relations. Normal arrows denote mass flows, circles at an arrow tail signify that the reactant participates catalytically in the reaction.

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