Figure 6

Testing misannotation candidates. TRII score distributions were examined for a set of 278 annAUGs that were likely to be misannotated based on sequence comparisons in 12 Drosophila species (red curve) [19–21]. Their score distribution (a) and cumulative distribution (b) are shifted toward the corresponding distributions for . The misannotation candidates distribution can be reconstructed by combining two distributions—0-upAUG and random—in proportions 31% and 69%, respectively, (green curve, see Methods).