Figure 1

Performance of Spellman et al.'s CDC score on Saccharomyces cerevisiae data. A specified number of genes are conserved as periodically expressed genes. These genes are compared with the published 104 cell cycle involved genes. The matched genes are counted. Most experimentally discovered cell cycle genes possess high periodicity scores. When the number of conserved genes is greater than 400, Spellman et al. method's identification ability degenerates, as shown by the flat tail of the curve.