Stability from Structure: Metabolic Networks Are Unlike Other Biological Networks

EURASIP Journal on Bioinformatics and Systems Biology

Table 1 Paper overview

Method label	Null model	Colored edges	SSS	Currency metabolites	Enzymatic regulation	Result section	Method section
A	ER	No	Prill	Present	No	3.1	—
B	Switching	No	Prill	Present	No	3.2	2.6
C	Switching	Yes	Prill	Present	No	3.3	2.7
D	Switching	Yes	BRENDA	Present	No	3.4	2.8
E	Switching	Yes	BRENDA	Removed	No	3.5	2.9
F	Switching	Yes	BRENDA	Removed	Yes	3.6	2.10

The "method label" is used throughout the paper for reference. The "null model" indicates the type of network model (i.e., topology) used to generate random networks in the enrichment analysis (see Section 2.6). SSS is the structural stability score (see Section 2.5). "Currency metabolites" indicates whether these metabolites have been considered in the motif count (see Section 2.9). "Enzymatic regulation" indicates whether the actual enzymatic reactions activity has been taken into account (see Section 2.10). Finally, "result section" and "method section" list the sections in which the method is first described.