Skip to main content
Figure 2 | EURASIP Journal on Bioinformatics and Systems Biology

Figure 2

From: Stability from Structure: Metabolic Networks Are Unlike Other Biological Networks

Figure 2

Schematic overview of the process of calculating the SSS. The motif in the top left corner is transformed to the adjacency matrix. Next, 10 000 Jacobians in steady state are generated by filling the nonzero entries of the adjacency matrix with values sampled from and distributions. In this figure, only four Jacobians are generated. Next the eigenvalues of all Jacobians are calculated. When all eigenvalues of a Jacobian are negative numbers with zero imaginary part, the steady state corresponding to that Jacobian is called (asymptotically) stable without oscillations. The SSS is the fraction of these steady states over all 10 000 steady states. Assuming that the four Jacobians in this example have the stability shown in the right of the figure, the SSS is 0.25.

Back to article page