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EURASIP Journal on Bioinformatics and Systems Biology
Figure 4 | EURASIP Journal on Bioinformatics and Systems Biology

Figure 4

From: Modelling Transcriptional Regulation with a Mixture of Factor Analyzers and Variational Bayesian Expectation Maximization

Figure 4

Simulated TF binding data. The figure shows simulated TF binding data. The vertical axis in each subfigure represents the 90 genes involved in the regulatory network. From left to right: (a) The binary matrix of connectivity between the 6 TF modules (horizontal axis) and the 90 genes, where black entries represent connections. Each module is composed of one or several TFs. (b) The real binding matrix between TFs (horizontal axis) and genes (vertical axis), with black entries indicating binding. (c), (d) The noisy binding data sets used in the synthetic study, with darker entries indicating higher values. Details can be found in Section 4.1.

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